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n = (Z² · p(1-p)) / e²1 − βα = 0.05

Design your study methodology and calculate sample size — powered by AI

From research question to IRB-ready protocol in one session. Gap analysis, methodology design, power analysis, and code generation — without waiting weeks for a biostatistician.

Start Your Research Plan — Free

5 free queries per month. No credit card required.

Sound familiar?

These problems cost researchers months of work and thousands in wasted funding.

Waiting weeks for a biostatistician consultation

Get sample size calculations in minutes, not weeks

Guessing which statistical test fits your design

AI recommends the right test based on your study parameters

Reviewer comments that your methodology is weak

Structured methodology with EQUATOR checklist compliance

Underpowered studies that waste months of work

Validated power analysis with generated code you can verify

How It Works
1

Research Gap Analysis

Systematically identify knowledge gaps across your field with AI-powered literature search and evidence appraisal.

2

Study Methodology Design

Get expert guidance on study design, including Target Trial Emulation, DAG confounding analysis, and EQUATOR reporting.

3

Biostatistical Analysis

Power analysis, sample size calculation, and statistical test selection with generated R/Python/STATA code.

4

Protocol Export

Export your complete research protocol as a formatted DOCX or PDF document with citations, ready for IRB submission.

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In blinded evaluation against GPT-5, ProtoCol scored significantly higher on statistical accuracy, ethical awareness, and code generation. See benchmark results

95% cheaper than legacy tools

Traditional statistical software charges thousands per year with no AI guidance.

ToolPriceAI GuidanceCode GenLit Search
nQuery$925–$7,495/yr———
PASS$1,095–$2,995/yr———
G*PowerFree———
ProtoColFrom $0/mo

Common questions

The short answer: yes, the calculations are real math — not AI guessing.

Stop guessing. Start designing.

5 free queries per month. No credit card. No biostatistician waitlist.

Start Your Research Plan

ProtoCol

AI-powered research methodology assistant

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Questions? Contact us at contact@protocol-research.com

Not for clinical decision-making. All protocols require expert review.